Naproxen and Ranitidine

Drug Interactions


naproxen and ranitidine

Is it ok to use Naproxen and Ranitidine together?

Naproxen (brand names include Aleve and Naprosyn) is a NSAID or nonsteroidal anti-inflammatory drug. It is used to treat pain, inflammation and fever. It is available in both over-the-counter and prescription formulations.

Ranitidine (and the brand name Zantac) is a H2 blocker. It reduces the amount of stomach acid produced. Common side effects include headache and nausea.

There is no interaction between immediate release formulations of naproxen and ranitidine. Ranitidine should be avoided with enteric coated forms of naproxen. The use of Zantac could cause the enteric coating to dissolve while still in the stomach.

Ranitidine may be recommended by your doctor to reduce the risk stomach damage from daily use of naproxen. This study has show ranitidine’s effectiveness at reducing damage from naproxen. NSAIDs like naproxen can increase the risk of bleeding ulcers.

Always speak with your doctor or pharmacist if you are uncertain about which medications you can use together. It is always a wise idea to verify medications are compatible.

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The pharmaceutical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education and should not be used as a substitute for professional diagnosis and treatment.
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