Can I take lansoprazole and ranitidine together? What is the difference between Prevacid and Zantac?
Lansoprazole (and the brand name Prevacid) is a medication from the family known as proton pump inhibitors (PPI). They affect the parietal cell and block the ability for it to produce stomach acid. The medication is usually well tolerated during short-term use with the most common side effects being diarrhea, nausea and headache. The PPIs are considered to be stronger than the H2 blockers, meaning they suppress more stomach acid.
Ranitidine (and the brand name Zantac) is a medication known as a H2 blocker. It also reduces the amount of stomach acid produced. It also is generally tolerated well when used for short periods of time.
Lansoprazole and ranitidine can be used together as no serious side effects or interactions have been identified. They both work to reduce the amount of stomach acid produced in different ways. Just because they can be used together doesn’t mean you should. If you are having symptoms severe enough to require two medications, a complete evaluation by a healthcare provider is warranted. I have seen people under a doctor’s care use both PPI like Prevacid and ranitidine safe and effectively. Long term use may cause Vitamin B12 and magnesium deficiencies.
Remember, long-term use of both the medications may result in certain vitamin and mineral deficiencies. Talk with your doctor or pharmacist to evaluate your risk.