Allopurinol and Azathioprine

Drug Interactions

What  is the  interaction between allopurinol and azathioprine?

Allopurinol is a Xanthine Oxidase Inhibitor. It is use to prevent gout and prevent certain types of kidney stone. It also use with some types of cancer treatments. The most common side effects include rash, diarrhea and nausea. Please contact your healthcare provider if a rash develops.

Azathioprine (and the brand name Imuran) is used to suppress the immune system. It is generally used to prevent kidney transplant rejection or for rheumatoid arthritis. It may also be use for other conditions (current research includes crohn’s, ulcerative colitis and IBD). The most common side effects include infection, nausea, diarrhea and reduction in certain types of blood cells.




It is recommend that allopurinol and azathioprine not be used together. Allopurinol can cause an increase of azathioprine in the body. That dramatically increases the risk of side effects. If you doctor determines it is in your best interest to use both medications, the dose of azathioprine with be lowered and you  will be closely monitored for side effects.

Always watch for side effects and interactions with medications. Please contact a healthcare provider if you feel you are experiencing side effects or drug interaction.

Comment Below! Because we’d like to hear your experience or further questions

Disclaimer

The pharmaceutical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education and should not be used as a substitute for professional diagnosis and treatment.
0 comments… add one

Leave a Comment