Loratadine and Chlorpheniramine Maleate Together

allergy medication

Can you take chlorpheniramine maleate and loratadine together?  Can you use both allergy medications at the same time? First off, loratadine is a newer second generation antihistamine and chlorpheniramine is an older first generation antihistamine (allergy medication).

Since these are both allergy medications, taking both is like doubling up.  That being said, I’ve seen people do well with both medications.  The loratadine is generally taken once a day, whereas the chlorpheniramine is take up to every 4 to 6 hours.  The main concern with using both would be increased drowsiness, dry mouth and potential mental confusion. If you are uncertain about taking the medications be sure to speak with your doctor or pharmacist.

The best results I’ve seen when people take both of these is when they take the loratadine once a day and then the chorpheniramine every 8 hours only as needed to control allergy symptoms.  Stretching out the chlorpheniramine maleate dose to every eight hours seems to reduce the incidence of side effects.  Be careful if you are using two allergy medications  at the same time, as it can make you drowsy and possibly slow your reaction time when driving.

If you have allergies so intense you feel the need to use two allergy medicines, I would encourage you to speak with your doctor and and determine the best treatment for you.

I hope you find this information useful.  Please always check with your doctor before starting new medications or changing existing therapy.  And, feel free to ask me and questions you may have about medications.

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The pharmaceutical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. This information is not intended to be patient education and should not be used as a substitute for professional diagnosis and treatment.
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